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Prevalence of polypharmacy and associated factors in older adults living in Rio Branco, Acre, Brazil: a cross-sectional population-based study, 2014

[Article in Portuguese, English]

Gustavo Rodrigues de Rezende 1Thatiana Lameira Maciel Amaral 2Cledir de Araújo Amaral 3Maurício Teixeira Leite de Vasconcellos 4Gina Torres Rego Monteiro 5

Epidemiol Serv Saude. 2021 May 31;30(2):e2020386.doi: 10.1590/S1679-49742021000200013.

Abstract 

Objective: To analyze polypharmacy prevalence and associated factors in older adults living in Rio Branco, Acre, Brazil, in 2014.

Methods: This was a cross-sectional population-based study using complex sampling with older adults. Polypharmacy was defined as concomitant use of five or more medications.

Results: Polypharmacy prevalence was 14.9% (95%CI 11.8;18.6), positively associated with females (OR=2.29 – 95%CI 1.41;3.74), white race/skin color (OR=1.61 – 95%CI 1.10;2.38), dependence (OR=1.65 – 95%CI 1.05;2.60), change in eating habits/dieting (OR=1.66 – 95%CI 1.16;2.36), hospitalization in the last 12 months (OR=1.61 – 95%CI 1.02;2.53) and presence of the following self-reported morbidities: systemic arterial hypertension (OR=2.40 – 95%CI 1.33;4.34), diabetes mellitus (OR=2.17 – 95%CI 1.23;3.84), osteoporosis (OR=2.92 – 95%CI 1.84;4.64) and heart problems (OR=2.94 – 95%CI 1.90;4.56).

Conclusion: This study found that polypharmacy in the older adults was associated with demographic and health conditions.